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To reduce the development of drug resistant bacteria and maintain the effectiveness of SUPRAX and other antibacterial drugsSUPRAX should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteriaWhen culture and susceptibility information are availablethey should be considered in selecting or modifying antimicrobial therapyIn the absence of such datalocal epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Hypersensitivity reactionAnaphylactic/anaphylactoid reactionsincluding shock and fatalitieshave been reported with the use of cefiximeBefore therapy with SUPRAX is institutedcareful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporinspenicillinsor other drugsDiscontinue use if a reaction occursClostridium difficile associated diarrheaEvaluate if diarrhea occursDose Adjustment in Renal ImpairmentThe dose of SUPRAX should be adjusted in patients with renal impairment and those undergoing continuous ambulatory peritoneal dialysis and hemodialysisCoagulation EffectsCephalosporinsincluding SUPRAXmay be associated with a fall in prothrombin activityProthrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicatedPhenylketonuricsSUPRAX Chewable Tablets contain aspartamea source of phenylalanine.

The dosage is based on your medical condition and response to treatmentIn childrenthe dose is also based on weight.

Clostridium difficile associated diarrheaCDADhas been reported with use of nearly all antibacterial agentsincluding Supraxand may range in severity from mild diarrhea to fatal colitisTreatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of Cdifficile

May potentiate carbamazepineanticoagulantsegwarfarinmonitorMay cause falseClinitestdirect Coomb’snitroprusside test for ketonesPotentiated by probenecid.

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tell your doctor and pharmacist if you are allergic to cefadroxil; other cephalosporin antibiotic such as cefaclor , cefazolin ancef, kefzol , cefdinir, cefditoren spectracef , cefepime maxipime , cefixime suprax , cefotaxime claforan , cefotetan, cefoxitin mefoxin , cefpodoxime, cefprozil, ceftaroline teflaro , ceftazidime fortaz, tazicef, in avycaz , ceftibuten cedax , ceftriaxone rocephin , cefuroxime zinacef , or cephalexin keflex ; penicillin antibiotics, or any other medications.

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